Calcium and magnesium content of rat liver and Morris Hepatoma 5123 tc.

Water and nitrogen contents were also determined. Measure ments were made on whole tissue, as well as on parenchyma. The hepatoma contained 79% water versus 71% in normal liver; the proportion of nitrogen in the solid matter of the tumor was higher than normal, indicating a decrease in non-nitrogenous compo nents, presumably glycogen and lipids. On either wet or dry weight basis, the hepatoma contained at least 100% more calcium and 25% more magnesium than normal liver. The calcium content appeared to increase progressively with in creasing age of the tumor. These results would not be anticipated on the basis of Coman's